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Whilst vitamin B12 side effects stomach-related are uncommon, some individuals experience mild gastrointestinal symptoms when taking supplements, particularly oral formulations

Studies demonstrate that NNMT inhibition "enhances fasting blood glucose levels, glucose tolerance, and insulin sensitivity" while reducing triglycerides and decreasing lipid deposition

If levels get too high, it can cause symptoms like shivering, diarrhoea, confusion, severe muscle tightness, fever, and even seizures

Leyrat, J

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So the typical response of a B12 shot for someone who needs it is that they feel great, it wears off, and they are back to their previous baseline