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454 Moreover, centrally mediated factors, such as cognitive processes (e.g., attention, distraction, catastrophizing), contextual beliefs about pain, and emotional states (e.g., depression, anxiety), significantly influence the pain experience
Research has identified both genetic and environmental factors, especially those involving fetal and early life development, in describing this complex condition
However, studies of the IGF system in cancer metabolism are still insufficient, not only the uptake and utilization of glucose, but also the mechanism of changes in lipid and amino acid metabolism still need to be explored
First, the overall gene expression patterns were visualized using principal component analysis (PCA), which revealed evident transcriptomic differences among the PBS, P-Mn@mHSA, and P-Mn/TI@mHSA groups, with no outlier samples detected (Fig
Herter, S