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Furthermore, the RMSF for sidechain and backbone showed elevated values due to the higher flexibility of the sidechains

Be patient and resist the urge to shake it, as this can break the delicate peptide bonds

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This means: No human PK reference data No human bioavailability data No human metabolism or clearance data Rodent-to-human PK extrapolation is therefore speculative This is a major context for research framing

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Freitas-Rodrguez, S., Folgueras, A