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Oxidative stress was studied in duodenal and sigmoid biopsies from 15 cirrhotic patients and 22 controls by analyzing transcription of genes involved in glutathione and uric acid metabolism using quantitative real-time polymerase chain reaction

Specifically, patients with Mrp2/Abcc2 gene polymorphisms may exhibit increased intestinal permeability

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However, studies on albumin administration in patients with stage II or higher HE was ineffective in resolving HE severity, ammonia levels, oxidative stress markers or cytokines, but it prolonged survival [77]

Deng WW, Yang X, Zhu Y, Yu JN, Xu XM

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