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AGEs can activate PKC through binding their specific receptor, namely receptor for advanced glycation end products (RAGE), which activates NOX and consequently ROS production

Phosphatidyl serine (PS) exposure on the outer leaflet of the erythrocyte membrane indicates storage lesions and the signals for apoptotic senescence [54]

Using digital camera, tubules were transferred into ISSA- special software for morphometrical analysis (Vamstec, Zagreb, Croatia)

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However, hair cell loss is not prevented due to the failure in lysosome formation

Physical Therapy stands out as a beacon of hope