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reported reduced expression of genes responsible for melanin synthesis in the hair folliclesuch as TYR, melan-A (MLANA), premelanosome protein (PMEL), TYRP1, SLC45A2, KIT, G proteincoupled receptor 143 (GPR143), and OCA2in patients with premature graying.15 UV radiation UV radiation plays an important role in hair graying by stimulating the production of free radicals
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Overall, these results show that a 3-month clinical intervention of L-GSH supplementation in T2DM subjects significantly improved the control of BCG infection within in vitro granulomas generated from PBMCs of T2DM subjects when compared to the placebo group
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