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Supports liver health: Enhances liver function and detoxification processes

In certain embodiments, any controlled release otic formulation or composition described herein increases the exposure of a therapeutic agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, or about 90% compared to a formulation or composition that is not a controlled release otic formulation or composition

In conclusion, various endogenous and exogenous pathophysiological mechanisms in patients with chronic kidney diseases lead to enhanced activity of oxidative enzymes such as xanthine oxidase (XO), myeloperoxidase (MPO), and the NADPH oxidase enzymes (NOX)

While the early data is exciting, it has not yet been approved for medical use and is only available through clinical studies

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The phosphorylated analogue of DSIP enhances slow wave sleep and paradoxical sleep in unrestrained rats