Fibroblast growth factor-21 (FGF-21) is one of the most important growth factors and plays an important role in the pathogenesis of metabolic diseases such as obesity and diabetes (Xu et al., 2009)
The agency also identified gaps concerning characterisation, impurities, aggregates, pharmacokinetics, toxicology and immunogenicity
Similarly, NSAIDs like diclofenac, used in veterinary medicine, have caused significant mortality in scavenging bird populations and indirectly affect human health through ecosystem imbalance and zoonotic transmission [58]
Concin N, Hofstetter G, Berger A, Gehmacher A, Reimer D, Watrowski R, et al
Nature Communications 5(1), 4625.CrossRefGoogle Scholar Zou, P, Zhao, Y, Douglass, AD, Hochbaum, DR, Brinks, D, Werley, CA, Harrison, DJ, Campbell, RE and Cohen, AE (2014b) Bright and fast voltage reporters across the visible spectrum via electrochromic FRET (eFRET)
clinical use is not established