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[2] [10] The primary histologic endpoint The primary endpoint was histologic improvement in MASH with no worsening of fibrosis

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They monitored IGF-1 levels, tracked insulin sensitivity, and conducted oral glucose tolerance tests

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Triggers of IL-1 production have been observed in a number of different stimuli, such as sulfur mustard, nickel, contact allergens or superantigens 36 IL-1 stimulates further release of secondary mediators, including IL-8

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