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doi: 10.3389/fphar.2025.1561351 Received 15 January 2025 Accepted 09 May 2025 Published 26 May 2025 Volume 16 - 2025 Edited by Ruyu Yao, Chinese Academy of Sciences (CAS), China Reviewed by Sharifah Alawieyah Syed Mortadza, Putra Malaysia University, Malaysia Alisson Mcario de Oliveira, State University of Paraba, Brazil Updates Copyright 2025 Zhi, He, Xue, Zhao, Gong, Guo, Luo, Tian and Dong
Three-dimensional brain organoids derived from human iPSCs, augmented with HIV-1susceptible microglia, recapitulate key features of human cellular diversity and permit direct visualization of neuroinvasion, including directed migration of infected microglia into neural tissue
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