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PI3K/Akt pathway promotes cell survival and protein synthesis

Oxidative damage and protection of the RPE

Since the vitamins are infused intravenously, they are absorbed by the body 100% compared to a much lesser percentage with oral vitamins

Importantly, resting extracellular polyamine concentrations are lower than needed to robustly exert NMDA modulatory effects, and NMDA receptor activation triggers extracellular Spd and Spm release in the striatum (Fage et al., 1992

On rest days, morning with food is the common timing

Without adequate levels of ALA, these enzymatic reactions stall, leading to a severe bottleneck in cellular energy production and an accumulation of metabolic byproducts like lactic acid