Storing a vial on its side or inverted keeps the solution in sustained contact with the rubber stopper, which pharmaceutical literature describes as a potential leachable-contamination pathway over extended periods
[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Wang G., Gong Y., Anderson J., Sun D., Minuk G., Roberts M.S., Burczynski F.J
After perforin forms pores in the cell membrane, granzyme B and other proteases enter the target cell and initiate programmed cell death (115)
Most patients describe it as a simple IV insertion
May require consistent hydration for best results
Users who expect dramatic results in one or two weeks from concentration increases will be disappointed, and may unnecessarily escalate further based on inaccurate assessment