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When combined with GHRP-6, the two compounds activate complementary pathways: GHRH primes and sustains the GH release signal while GHRP-6 amplifies the pulse amplitude

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(11) Elena M Khvatova, Victor N Samartzev, Pavel P Zagoskin, Igor A Prudchenko, and Inessa I Mikhaleva (2003) Delta sleep inducing peptide (DSIP): effect on respiration activity in rat brain mitochondria and stress protective potency under experimental hypoxia Peptides, 2003 Feb, Volume 24 (Issue 2), Pages 307-11

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However, this increase is accompanied by a significant shift in NK cell subsets