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Several things could be happening: The vial might be too cold

You have no idea if the product you're buying is pure, under-dosed, or even contains the correct substance at all

Mix it in cold water or milk for a healthy shake, blend it with yogurt and fruits for a delicious smoothie, or add it to different preparations like pancakes, acai bowls, muffins, etc

Senolytic FOXO4-DRI can inhibit FOXO4 binding by disrupting the p53-FOXO4 interaction and selectively cause apoptosis via p53 nuclear exclusion in senescent cells and aging mouse models, which may be a promising approach for preventing senescence 11

You can reduce your risk by avoiding unnecessary high doses, especially if your body does not need extra B12