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The anti-HTN effects of ginger rhizome extracts in rats involve mechanisms such as NO and PGI 2 release, activation of cGMPK + ATP -channels, stimulation of muscarinic receptors, and Ca 2+ -release from intracellular stores via transmembrane CCs (570, 571)

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Usually temporary effect normalizing after 1-2 weeks

10.1371/journal.pone.0078627 PLoS One 146 SatakeW.NakabayashiY.MizutaI.HirotaY.ItoC.KuboM.et al (2009)

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Only trained professionals should handle this peptide in controlled laboratory environments