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Data availability Data were depositing in a public repository and any one can access it using this link ([Data Analysis of vildaglibtin + docosa](https:/pharmtantaedu-my.sharepoint.com/:f:/g/personal/naglaa_khedr_pharm_tanta_edu_eg/EqONO5Ti0zBEr5rSQAbKuNQBjXotoZv81TH2z_yEmBlkig?e = ADPqUi)) or from the corresponding author: Naglaa Khedr

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In relation to SIRT5, it was determined that this protein exerts a suppressive effect on peroxisomal FAO by means of the inhibition of Acyl-CoA oxidase 1 activity, both in vitro and in rodent liver tissue (Chen et al