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The first characterization of ABT-737, an inhibitor of BCL-W, BCL-XL, and BCL-2, has been shown to specifically induce apoptosis in senescent cells in a BCL family-dependent manner (60)

Groh et al., 2016

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There are two prospectively randomized trials on either Vemurafenib alone (BRIM8) or the combination of Dabrafenib and Trametinib (COMBIAD) [2, 9]