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Schrader M., Kamoshita M., and Islinger M., Organelle InterplayPeroxisome Interactions in Health and Disease, Journal of Inherited Metabolic Disease 43, no

Mechanistically, podocyte-specific LONP1 deficiency induces mitochondrial homeostasis imbalance and dysfunction, leading to podocyte injury and glomerulosclerosis [121]

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dysbiosis contributes to systemic inflammation and chronic diseases

Discussion Here we show that zonula occludens toxin (Zot, or zonulin), a potent regulator for intestinal TJ competency and intestinal barrier function, is controlling the onset of murine and human arthritis