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doi: 10.1016/j.chom.2023.05.007

Tanaka, S., Hayakawa, K., Umetani, Y

These data demonstrate that H 2 O 2 induces TM3 Leydig cell senescence in vitro and that, in these senescent Leydig cells, FOXO4 is translocated to the nucleus and activates a senescence-associated pathway

These compounds can mimic hormones, bind to hormone receptors, and exert either agonistic or antagonistic effects, thereby disrupting steroidogenesis and interfering with neurogenesis, synaptic transmission, and brain sexual differentiation ( Dysregulation of the neuroendocrine system can adversely affect learning, memory and behavior, potentially leading to neurodegenerative diseases

This active vial should be considered to have a very finite lifespana few days, maybe a week at most

Copper binding by tetrathiomolybdate attenuates angiogenesis and tumor cell proliferation through the inhibition of superoxide dismutase 1