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XCT can import cystine (CySS) into the cell, which can be reduced to cysteine (Cys) using GSH or thioredoxin reductase 1 (TXNRD1)

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Surviving OLs in acute lesions show dying back of processes with intact somas, suggesting sub-lethal injury that may precede their subsequent progressive loss 10

Maintenance treatments are required to keep the new skin's tone fair and healthy