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Severe oxidative stress at the intestinal mucosa may lead to the loss of tight junction proteins through processes including the thiol oxidation, nitration, phosphorylation, and carbonylation of cytoskeletal proteins, tight junction proteins, and intracellular regulatory proteins 89

LATIN AMERICA GLUTATHIONE MARKET SIZE, BY PHARMACY, 2018-2032 (USD MILLION) TABLE 278

Mirhosseini H, Maayeshi N, Hooshmandi H, Moradkhani S, Hosseinzadeh M

This process is carried out by the cytochrome P450 enzyme system, specifically the CYP2D6 enzyme

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