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doi: 10.1016/j.cell.2024.01.030 19 ConradMPrattDA

The first is Huppke-Brendel Syndrome, a severe neurodevelopmental disorder characterized by severe intellectual disability, motor deficits, and progressive neurodegeneration

2) the data was already published in another article identified in the search

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Furthermore, a placebo-controlled randomized trial evaluated the efficacy of folinic acid (5 mg twice daily) for 12 weeks in 19 children aged 310 years (sex distribution not reported) with ASD diagnosed by ADOS, without genetic syndromes, major medical comorbidities, or treatments affecting folate metabolism

This inhibitory effect is hypothesized to reduce irrelevant attention (and subsequent behaviors), resulting in an improvement in a patient's focus and correcting deficits in attention (Bidwell et al, 2010)