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A variante sinttica, BPC-157, um pentadecapeptdeo composto por 15 aminocidos extrados da protena BPC, demonstrou reter diversos atributos teraputicos de sua molcula precursora

Additionally, the pocket normally occupied by the conserved phenylalanine residue of the TIN2 F-X-L-X-P motif was fully obstructed by a crystal contact with a TRF1 TRFH copy in an adjacent asymmetric unit, further limiting the possibility of obtaining XChem hits outside of the leucine pocket

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doi:10.1146/annurev.biochem.72.121801.161828

Conversely, bile acids also affect the gut microbiota through activation of the innate immune system and production of antimicrobial peptides (127)