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Their lengths tend to diminish with repeated cell replication and aging [2]

Blood was flushed out with 150 mL of saline with 100 U/L heparin at 30 mL/min, followed by perfusion with 3% formaldehyde and 150 mL of 1% glutaraldehyde solution

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A 2025 systematic review reported 7 of 12 maintained improvement beyond 6 months

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doi:10.26355/eurrev_202008_22477