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Melanoma cells at metastatic and therapy-resistant stages display increased oxidative phosphorylation and a heightened capacity to maintain redox balance

The gene expression data from Pickart and colleagues provides the most compelling mechanistic context here

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Bacterial cell extracts were treated with the thiol-alkylating agent monobromobimane (mBBr) to facilitate the detection of Cys-Gly and other thiol-containing metabolites