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Theo Haradis has done where mast cells and microglia also mediate the fear pathways, change the limbic system, change the amygdala literally our perception of what is a threat in the world is distorted

Of note, the methodology of this healing evidence (Klicek et al., 2008

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Rather than targeting fat cells directly, it intervenes in the brain's hunger-satiety circuitry, reducing the drive to eat