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The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript

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( Reference Norlund, Grubb and Fex 29 ) demonstrated a significant correlation between plasma Hcy and serum creatine, and suggested that creatine turnover may be a factor determining Hcy levels

If a compound or molecule has low pK (less than 2.5), it has low affinity for binding protons

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