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Furthermore, in a phase II study, the combination of chemotherapy (albumin-bound paclitaxel and gemcitabine) along with pegvorhyaluronidase alfa (PEGPH20), an agent designed to degrade hyaluronan, has been shown to improve progression-free survival in pancreatic cancer patients, especially those with hyaluronan-high tumors [136]

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The research protocol got approval from the Zagazig University Animal Care and Use Committee (code number ZU-IACUC/3/F/228/2022)

And berberine can interact with certain medications, so its important to speak to your healthcare provider before starting berberine

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