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The pathogenesis of OA is poorly understood and there is a lack of therapeutic interventions to reverse the pathological process of this disease

10.5124/jkma.2017.60.5.358 46 ChangJ.ZhangY.LiY.LuK.ShenY.GuoY.et al

Vitamin B12, or cobalamin, is naturally found in animal foods

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However, uridine supplementation in aged oocytes significantly reduced gene expression in these pathways and upregulated genes involved in mitochondrial oxidative phosphorylation (Fig