[36] Muscle Tone Low muscle tone in the gut, often tied to mitochondrial dysfunction, can lead to constipation because the muscles in the intestines arent able to contract efficiently
To test this, lineage-negative cells isolated from Mx1-T3 and Mx1-Cre mice treated with or without -glucan were differentiated into myeloid cells ex vivo, treated with or without -glucan, and subsequently stimulated with LPS (Extended Data Fig
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