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The expression of ACSL4 upregulation is considered a biomarker and contributor to ferroptosis, it can esterify free polyunsaturated fatty acids into membrane phospholipids with the help of lysophosphatidylcholine acyltransferase 3 (LPCAT3)

Cell death in drug-induced liver injury

lowest doses and results showed that doses higher than 2 mg/day are more effective on reducing insulin levels

Extensive experiments have provided substantial evidence for the effectiveness of various natural substances, such as Polygonum multiflorum, Artemisia annua leaves, berberine (BBR) [13], and curcumin, in alleviating MASLD

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

Kirti A, Simnani FZ, Jena S, Lenka SS, Kalalpitiya C, Naser SS, et al