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Open questions include tissue-selective delivery, chronic dosing effects on one-carbon metabolism, and interactions with NAD precursor strategies [14,8,9]

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Fortunately, there is increasing evidence that oral B12 supplements are just as good as injections for raising blood levels in most people ( Vegetarians and vegans are usually advised to take at least 10 mcg per day, or at least 2,000 mcg once per week ( However, some doctors still prefer the use of injections

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