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Dis Esophagus 35(4):doab081, 2022

AHK-Cu's vascular mechanism delivers results that pure structural peptides cannot replicate

The main ROS derived from aerobic metabolism include hydrogen peroxide (HO), superoxide radical (O), hydroxyl radical (OH), and singlet oxygen ( 1 O), whose overproduction emphasizes the gaps in understanding the spatiotemporal regulation and hierarchy of ROS-induced cellular damage (Sies and Jones 2020

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The indirect costs of IC/BPS, including time away from work and lost productivity while working, are particularly significant since the condition primarily affects working age adults, and especially women aged 25-50 years