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23 Supplementation of 1 mg daily is recommended for patients with specific risk factors (e.g., bariatric/gastric surgery patients, those with severe malnutrition, chronic alcohol use, chronic hemolytic anemia and conditions with high cell turnover, and use of antimetabolite medications such as methotrexate)

Wang Z et al

Depending on the severity of the deficiency, synthetic forms of vitamin B can bring levels back to normal

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X., Dixon, J

Vitamin B12 Deficiency Your body stores 1,000-2,000 times as much vitamin B12 as you'd eat in a day, so it can take many years to see symptoms of vitamin B12 deficiency