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Though the etiology of hyerplastic process of BPH is clearly not known, but many partially overlapping and complementary theories have been proposed for the overgrowth of smooth muscle tissue and glandular epithelial tissue like aging: late activation of cell growth [5], defective cell death and hormonal changes

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In turn, various physiological abnormalities contribute to the characteristic symptoms of COPD chronic cough and sputum production and dyspnea

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