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Experimental in vitro models comprise a wide range of cell types and culture procedures, including primary hepatocyte cultures, differentiated hepatic cell lines, stem cell derived hepatocytes, cultured on two- (2D) or three-dimensional (3D) formats, which can significantly influence the outcome of the experiment

10.1371/journal.pone.0115694 31 ChenJ.ZhuT.YuD.YanB.ZhangY.JinJ.et al (2023)

Parazzini F, Chiaffarino F, Surace M, Chatenoud L, Cipriani S, Chiantera V, et al

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Abbreviations: IR: insulin resistance