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Combined psychological and pharmacological approaches often yield better outcomes than either alone

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Finally, future research should examine the correlation between psychological factors, such as stress, depression, and cognitive interference, and oxidative stress in ED

The interaction is facilitated by the microbiota, but a dysbiotic biota can lead to brain inflammation and psychopathologies as depicted in Figure 6 (86, 87)

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Glycocalyx degradation after cardiac arrest and resuscitation in rats induces vascular endothelial adhesion factor (VCAM-1), intercellular cell adhesion molecule-1 (ICAM-1), iNOS, and COX-2 expression, exacerbating neuronal loss, glial activation, and brain edema