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Meanwhile, 16 core targets were identified by PPI network analysis

(Beetroot antioxidant action) Clifford T, Howatson G, West DJ, Stevenson EJ

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Anyone with metabolic, cardiac, GI, hepatic, or renal disease or who is pregnant, breastfeeding, or planning pregnancy should not consider it without licensed clinical care

Bryan, N.S., Petrosino, J.F

Patients require evaluation before starting DMARDs to rule out contraindications to the medications (meaning the patient should not take a certain medication due to the harm it would cause) and monitoring while using them to watch for serious side effects