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When Tregs function properly, they produce IL-10 and TGF-beta, cytokines that actively suppress mast cell degranulation

In the end, this can hold a general counteracting potential and contributing innate neurotransmitter potential, matching with the original cytoprotection concept perception holding equal cell protection (necrosis prevention) against a variety of different agents, thus, a pleiotropic beneficial effects that should be obtained with cytoprotective agents application that could also have neurotransmitter background as well

2021 Mar;42(3):305-13

Heatshock Protein (HSP) Family Expression Is Dichotomous and Prognostic in Acute Myelogenous Leukemia (AML)

Moreau, Eric J