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However, certain skincare products may increase irritation when used together: Retinoids (Tretinoin, Adapalene) May increase skin sensitivity

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Ferritin upregulation inhibits estradiol synthesis via the NF-B/iNOS pathway and downregulates the Nrf2/GPX4 pathway, exacerbating ovarian damage (Sze et al., 2022)

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Berberine Protects Immortalized Line of Human Melanocytes from H2O2-Induced Oxidative Stress via Activation of Nrf2 and Mitf Signaling Pathway