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3 University of Pittsburgh Asthma and Environmental Lung Health Institute, Pittsburgh, Pennsylvania, USA

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Experimental observations indicate that the combination allows investigation of complementary pathways in tissue regeneration, including vascular growth, fibroblast recruitment, matrix reorganization, and cellular protection

The rigid, insoluble strands form fibers which align in parallel, creating intracellular crystals (Inusa et al., 1985

Cao et al., 2017) and increase susceptibility to pathogenic infiltration (Desai et al., 2016) (Figure 1)