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Oxidative stress in obesity: A critical component in human diseases

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Dis.,148:689-694 (1993)

Thus, while mitochondria are critical elements involved in the signaling cascade toward APAP-induced cell death, the organelle also plays an important role in the recovery and regeneration of liver function, especially in hepatocytes away from the central vein at the borders of the area of necrosis83

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First, using an HCT116 xenograft model, we show that repeated 5FU treatment (10 mg kg 1 d 1 for 7 days) promoted increased TOM20 abundance (Fig