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Kynurenines and depression in other neurobiological conditions Alterations in KYN metabolism extend beyond MDD and have been implicated in a range of neurobiological conditions associated with depressive symptoms, such as bipolar disorder, schizophrenia, Alzheimers disease, and acquired brain injury

Simeon 2000 Life Sci simultaneously documented the stimulation of matrix repair and the suppression of degradation by MMP-2 and MMP-9 (matrix metalloproteases), a unique profile of constructive rather than destructive remodelling

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Dysbiosis signature in DKD: SCFA-producers (Roseburia intestinalis, Faecalibacterium prausnitzii), Proteobacteria (Escherichia-Shigella), Bacteroides stercoris, Gemmiger (169, 190)

Influence of large hiatus hernia on cardiac volumes