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Gill, S

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(4) After cell stress or injury, these cells are posited to activate innate immune pathways, especially Toll-like receptor (TLR) signaling, which may drive inflammatory responses inside the cell

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For example, a study of inter-relationship between MTHFR polymorphism and MDD found that the minor T-allele of MTHFR C677T was associated with increased folate deficiency-related body mass index and homocysteine levels in MDD patients only 72