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The L66 mouse line, which overexpresses the full-length human tau with double mutations (P301S/G335D), demonstrates reduced nest building and sucrose preference at 5-6 months old, suggesting apathy-like deficits (Robinson et al., 2024)

Figure 7 3.2.3.4 UPF additives induced depression The additives and flavoring compounds which are used in UPF production have been associated with a higher risk of depression (101)

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In the normal control group, histopathological alterations were observed, indicating potential baseline vulnerability in neuronal regions

The electrolyte imbalances likely arise as a result of damage to the lens cell membranes, especially those of the lens epithelial cells, which play the major role in maintaining the ionic and metabolic homeostasis of the entire lens