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Description

In particular, TP53 mutation connects with raised expression of genes involved in mevalonate pathway in human breast cancer, and most importantly, mutant TP53 upregulates these genes and activates the mevalonate pathway, which is indispensable to keep the malignant status of breast cancer (178)

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Exploring such diagnoses is important, as genetic malfunction may also be manifesting in less visible systems e.g., impact on the cardiovascular, autonomic, gastro-intestinal and urogenital systems

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doi: 10.1080/24750573.2018.1517466 21 OkuyucuMCeylanMFTural HesapciogluSKonyaliogluFSFirat OguzENeseliogluS

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