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Suwatvitayakorn P, Ko MS, Kim KW, Chanpiwat P

Their high receptor specificity and relatively low toxicity profiles (compared to small molecules or full-length proteins) have made them central to 21st-century drug discovery

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As part of its anti-inflammatory effect, GHK-Cu is known to suppress free radicals, thromboxane formation, transforming growth factor beta-1, tumor necrosis factor-alpha, and protein glycation

Notably, the occupancy of H2AK119ub at Bdnf promoters I, II, IV, and VI was decreased, while only the occupancy of H3K27me at Bdnf II and VI was found to be reduced by BHBA in our previous study (Zhou et al., 2008)