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[14] Serious systemic side effects have not been reported

Patients should compare total cost across alternatives, including modern combination protocols, when planning a 6 to 12 month treatment cycle

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The acylated side chain and amino acid substitutions that extend in-vivo half-life also improve storage stability

10.1038/s41598-018-26632-w 110 ZhangX.BowenE.ZhangM.SzetoH

Indeed, the GSH and GSH-related enzymatic systems are efficient tools that cells have exploited in detoxification and, at the same time, represent the most ancient notice on the physiological role played by the tripeptide