This review provides in-depth details of the molecular mechanisms by which paracellular permeability is regulated, with relevance to disease conditions of the gastrointestinal tract
53 Functional impact means selfreported or observed increases in the amount of time it takes to independently complete complex activities of daily living, whereas functional impairment describes more noticeable difficulties with everyday tasks
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Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)