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Toxicol Sci 137:1225 Marx V (2013) Targeted proteomics

Orforglipron: Eli Lilly oral GLP-1 The most significant development is orforglipron, Eli Lilly oral GLP-1 receptor agonist

Pharmacol Res 109:119131

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Ghasemi A., Tohidi M., Derakhshan A., Hasheminia M., Azizi F., Hadaegh F

Newer agents are being sought to avoid kidney and metabolic dysfunction

This involves the increased production of reactive oxygen species (ROS) and a concomitant impairment of antioxidant defenses, such as glutathione [6, 7]